Upcoming Events
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Oct
31
MCB Cell and Developmental Biology Journal Club 12:30pm
MCB Cell and Developmental Biology Journal Club
Thursday, October 31st, 2024
12:30 PM - 01:30 PM
TLS 263
This week in Cell and Developmental Biology Journal Club, Rosie Mirabella will lead a discussion of “STING directly recruits WIPI2 for autophagosome formation during STING-induced autophagy” by Wan et al., 2023.
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Nov
1
CANCELED: MCB Research in Progress: Dan Phillips 12:20pm
CANCELED: MCB Research in Progress: Dan Phillips
Friday, November 1st, 2024
12:20 PM
BPB 130
Dan Phillips
Gogarten LabThe Cyanobacterial dnaX intein
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Nov
1
MCB Faculty Meeting 1:30pm
MCB Faculty Meeting
Friday, November 1st, 2024
01:30 PM
Kresge TLS 263
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Nov
4
MCB Micro Journal Club 4:00pm
MCB Micro Journal Club
Monday, November 4th, 2024
04:00 PM
BPB 401
Sønderholm, M., Kragh, K. N., Koren, K., Jakobsen, T. H., Darch, S. E., Alhede, M., Jensen, P. Ø., Whiteley, M., Kühl, M., & Bjarnsholt, T. (2017). Pseudomonas aeruginosa Aggregate Formation in an Alginate Bead Model System Exhibits In Vivo-Like Characteristics. Applied and Environmental Microbiology, 83(9), e00113-17. https://doi.org/10.1128/AEM.00113-17
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Nov
5
MCB Seminar Series: Emma Watson 3:30pm
MCB Seminar Series: Emma Watson
Tuesday, November 5th, 2024
03:30 PM
BPB 131
Emma Watson
Assistant Professor, Department of Systems Biology
University of Massachusetts, Chan Medical School
Host: Andrei AlexandrescuChromosomal structure and function in cancer
Over 90% of cancer genomes have abnormal chromosomal composition, deviating (often significantly) from the normal 46 chromosomes in healthy cells. Chromosomes can be gained, lost, broken, and fused together during tumor genome evolution, with genomes ultimately converging on a set of features that are enriched in a tumor type-specific manner, for instance, +1q and +8q in breast cancer. We utilize in vitro approaches to model karyotype evolution in cancer and build tumor genomes in the lab from healthy diploid genomes. We use these models to uncover structural facilitators and functional drivers of these common chromosomal abnormalities in cancer.
About Dr. Watson:
Dr. Emma V. Watson obtained her B.S. in Biophysics from UConn, studying protein folding with Dr. Andrei Alexandrescu, and received her Ph.D. in Biomedical Science from UMass Chan Medical School studying metabolic gene network regulation with Dr. A. J. Marian Walhout. For her thesis work, Dr. Watson received an American Heart Association fellowship and the Harold M. Weintraub Award. Dr. Watson was a Damon Runyon Postdoctoral fellow in Dr. Stephen J. Elledge’s lab at Harvard Medical School, where she uncovered oncogenic roles of chromosomal abnormalities in cancer. Dr. Watson opened her lab at UMass Chan Medical School in 2022 where she focuses on cancer genome structure and function.Publications:
Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns
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Computational Biology Core Data-Therapy session (10 July, 10:30am) : Join us with your questions for General Consultation. Join remotely with WebEX: https://uconn-cmr.webex.com/meet/vis16107 @UConnMCB @UConnCAHNR @UconnMars @uconneeb @UConnGOMCB
Tomorrow!
really great fellowship to support if you can! Designed to recruit/support underrepresented minority scientists to @UConnMCB @UConnGOMCB
Linda D. Strausbaugh Fellowship in Genetics and Genomics https://uconn.networkforgood.com/causes/3058-linda-d-strausbaugh-fellowship-in-genetics-and-genomics
Grad students, we often do the mentoring, so def check out #BlackInTheIvory too
@R_Duggan_ @RoseDziedzic @jdtamucci @nidhi_vijayan @kampamycin @eaherder @Dvorhagen @ScienceyNeitzey @Sean__Gosselin @TonysPants @CalabreseJoshua @megaw_att @TheManWhoTests @katiee_kyle @EG_Microbio
News and Notes
Coffee Hour! 05/09Come join us for the first coffee hour in person since COVID started. Monday the 9th from 10-11 on the second floor of BPB. Hoping to see you there!